Introduction and Background: Infection with the Nipah virus is fatal infection of epidemic potential. It tcan be transmitted through animal to human or human to human route. Even with a case fatality rate of 94.7%, early treatment and prompt control activities by medical professionals can save more lives. In the past, India has witness the outbreak of the disease in some states. With this background it is important to assess the knowledge of B.Sc. nursing students regarding Nipah virus infection.

Material and Methods: In this interventional study 80 B. Sc. nursing students were selected conveniently from selected nursing colleges in Haryana. A 25 items questionnaire was used to assess of the knowledge of undergraduate nursing students regarding Nipah virus infection. Pretest was conducted before providing structured information module followed by post test conducted 7 days after the administration of structured information module to assess the effectiveness of intervention.

Result: Majority of the B.Sc. Nursing students (70%) belonged to the age group of 17-20 years and were female (81.25%). 27.5% of the students were studying in BSc Nursing I Year course followed by 26.25% in B. Sc. Nursing II year course. Majority 85% of the students had no previous exposure to knowledge regarding Nipah virus. In the pre-test, 63% of the students had poor knowledge followed by 11% had average knowledge and only 6% had good knowledge. In the post-test 67% of the students had good knowledge followed by 10% had average knowledge and 3% had poor knowledge.

The mean pretest knowledge score was 11.32±2.22 that is less than the 50% of the maximum score. It increased significantly in posttest to 21.63±4.32 which signifies the effectiveness of structured information module.

Conclusions: The study showed that structured information module was effective to enhance the knowledge of nursing students regarding Nipah virus infection.